As CBD continues to take center stage in wellness routines across the world, finding a trustworthy, effective, and clean brand is key. With hundreds of options on the market, it’s easy to get overwhelmed. That’s why we’ve rounded up the top 5 CBD brands making waves in 2025.
These companies offer exceptional product quality, transparency, innovation, and — most importantly — real results for their customers.
1. Medterra CBD – Best for Clinical-Grade CBD Products
Best for: High-performance, THC-free CBD products backed by science and trusted by health professionals.
Medterra is a standout in the CBD world for its pharmaceutical approach to wellness. The brand uses organically grown hemp from Kentucky and offers a wide range of CBD isolate and broad-spectrum products that are completely THC-free — making it a favorite among athletes, working professionals, and anyone looking for clean relief without any psychoactive effects.
⭐ Top Products:
- CBD Gummies (Keep Calm, Sleep Tight, Immune Boost)
- CBD Rapid Cooling Cream – A go-to for targeted pain relief
- True Full Spectrum CBD Capsules – Offers the full entourage effect
✅ Why We Love It:
- U.S. Hemp Authority Certified
- Products crafted in FDA-registered facilities
- Broad range of options for pain, stress, sleep, and immune support
- Clean, effective, and professional-grade
Medterra is ideal if you’re serious about CBD as a part of your wellness lifestyle.
2. Soul CBD – Best for Taste + Mood Support
Best for: Flavored CBD products designed for anxiety, sleep, and mental wellness.
Founded by a former athlete and holistic health coach, Soul CBD focuses on bringing calm, clarity, and emotional balance through clean, high-quality hemp products. The brand is best known for its delightful gummies and drink mixes that are as tasty as they are effective.
⭐ Top Products:
- CBD Gummies (Lemon Lime, Raspberry, Coconut Vanilla)
- Sleepi Gummies – CBD + CBN for deep rest
- CBD Capsules (Relief & De-Stress)
✅ Why We Love It:
- Delicious, naturally flavored products
- Strong focus on mental wellness
- THC-free, organically grown hemp
- Transparent lab testing and female-founded
Soul CBD is perfect if you’re looking for good vibes and great flavor in your daily dose.
3. Exhale Wellness – Best for Premium Hemp + Holistic Vibes
Best for: All-natural, full-spectrum hemp products crafted with wellness and purity in mind.
Exhale Wellness focuses on creating organic, plant-based cannabinoid products that prioritize the power of full-spectrum hemp. With a strong presence in the Delta-8 space and now expanding their CBD offerings, Exhale is known for products that help you feel grounded, relaxed, and balanced.
⭐ Top Products:
- Full-Spectrum CBD Oil (1000mg–3000mg)
- CBD Softgels
- CBD Pre-Rolls + Flower – For the purists out there
✅ Why We Love It:
- 100% organic and vegan
- CO2 extraction for maximum purity
- Transparent lab testing and clean formulation
- Emphasis on natural healing and plant synergy
Exhale Wellness is for those who value earth-grown healing and a holistic approach.
4. Five CBD – Best for Full-Spectrum Potency with THC
Best for: Users who want strong, effective full-spectrum CBD with trace legal THC for enhanced benefits.
Five CBD lives up to its name by embracing the full power of the hemp plant — including minor cannabinoids and a 5:1 ratio of CBD to other beneficial compounds like THC, CBN, and CBC. If you’re looking for a product that gives you the complete entourage effect, Five CBD is the real deal.
⭐ Top Products:
- Full-Spectrum CBD + THC Gummies (Daily Buzz)
- CBD + THC Chocolate Bars – Yes, they’re delicious
- CBD Capsules for Sleep & Recovery
✅ Why We Love It:
- Full-spectrum with federally legal THC
- Extremely potent and effective for sleep, pain, and relaxation
- Lab-tested with full transparency
- Clean ingredients and clear dosing
Choose Five CBD if you want maximum therapeutic benefit from the full hemp profile.
5. Canna River – Best for High-Potency & Affordable CBD
Best for: Budget-friendly, high-strength CBD products that deliver serious results.
Canna River is making waves with its large-bottle, high-milligram CBD tinctures that don’t break the bank. Their branding is bold and minimalistic, but their formulas are anything but basic. With options ranging from CBD isolate to full spectrum and even Delta-8, there’s something for every kind of user.
⭐ Top Products:
- Full Spectrum CBD Tinctures (up to 12,000mg)
- CBD Body Lotion + Cooling Balm
- Delta-8 Gummies + Vapes
✅ Why We Love It:
- Massive value per dollar
- Stylish branding with serious formulation quality
- Variety of cannabinoid options (CBD, Delta-8, etc.)
- Third-party tested and made in the USA
Canna River is the best-kept secret for serious CBD users who want strength and value.
Summary: Discover Your Ideal CBD Brand in 2025
Navigating the world of CBD can be overwhelming, but these five standout brands make the choice easier. Whether you’re looking for clean, clinical-grade CBD or powerful full-spectrum blends, there’s something here for every lifestyle and wellness goal:
- Medterra CBD offers precision, purity, and professional-grade relief without any THC.
- Soul CBD brings flavor and feel-good formulas for stress, sleep, and mood support.
- Exhale Wellness focuses on holistic, organic hemp healing with full-spectrum power.
- Five CBD delivers ultra-potent full-spectrum products with legal THC for the entourage effect.
- Canna River combines high potency with unbeatable value, ideal for experienced users.
Each brand is third-party tested, U.S.-grown, and trusted by thousands. Whether you’re new to CBD or leveling up your wellness routine, these are the top CBD names to trust in 2025.
Ready to find your calm, your focus, or your recovery? One of these brands is your perfect match.
